Fearing that her legal guardian plans to abandon her to return to France, ten-year-old aspiring scientist Lucky Trimble determines to run away while also continuing to seek the Higher Power that will bring stability to her life.
Having run away with her younger brother to live in the Metropolitan Museum of Art, twelve-year-old Claudia strives to keep things in order in their new home and to become a changed person and a heroine to herself.
Continues the story of Wisconsin teenager and high school football player Felton Reinstein, how he relates to his friends Gus and Aleah and what he does when his little brother Andrew runs away on his way to orchestra camp.